Forty-four patients with Japanese cedar pollinosis were administered B. longum BB536 powder (100 billion /day) or a placebo powder for 13 weeks, beginning about one month before cedar pollen became airborne.
In the patients who consumed B. longum BB536, their subjective symptoms were remitted and blood markers improved. Improved symptoms were also observed in a clinical trial using yogurt containing B. longum BB536.

Total scores of medicalsymptoms during pollen season  Changes in blood markerduring the study period

In vitro experiments, animal studies, and clinical trials suggest that the efficacy of B. longum BB536 is manifested both through direct stimulation by the bacterial bodies on the intestinal immune system and through the functions of B. longum BB536 to maintain intestinal health.

Anti-allergy mechanism of B. longum BB536

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