Fifteen infants with atopic dermatitis due to milk allergy were given milk with B. breve M-16V added. As a result, the proportion of bifidobacteria in the intestinal flora was increased and the symptoms of atopic dermatitis were relieved.

Proportion of bifidobacteria after B. breve M-16V administration  Changes in atopic dermatitis symptom scores after B. breve M-16V administration

The anti-allergy activity of B. breve M-16V in animals was compared with that of other bifidobacterial strains and lactic acid bacteria. B. breve M-16V was found to be the most potent for anti-allergy.

Effects of different probiotics on allergy reactions
 : Significantly improved,
 : No significant difference compared with the control group;
 : Not tested

Skin reaction: Acute allergic reaction diagnosed by auricular swelling Bronchoconstriction response: Allergic reaction to methacholine (bronchoconstrictor) Eosinophil, IL-4, IL-5, IL-10: Counts in bronchoalveolar lavage fluid IgG1: OVA-specific IgG1 level in blood

B. breve M-16V is also a selected strain of bifidobacteria.

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